Faculty

David Agard

agard@msg.ucsf.edu

Professor, Biochemistry and Biophysics

Research summary: Structure, function, and folding of proteins, chromosomes, and centrosomes

http://www.msg.ucsf.edu/agard

Kaveh Ashrafi

kaveh.ashrafi@ucsf.edu

Associate Professor, Physiology

Research summary: Molecular mechanisms of energy balance and neurobiology of feeding behavior

http://ashrafilab.ucsf.edu/

Patricia Babbitt

babbitt@cgl.ucsf.edu

Professor, Bioengineering and Therapeutic Sciences, Pharmaceutical Chemistry

Research summary: Computational and experimental analysis of protein superfamilies for functional inference and enzyme design

http://babbittlab.compbio.ucsf.edu/

Frances Brodsky

frances.brodsky@ucsf.edu

Professor, Bioengineering and Therapeutic Sciences

Research summary: Intracellular Membrane Traffic: Mechanisms & Immune Function

http://brodsky.ucsf.edu/

Al Burlingame

alb@cgl.ucsf.edu

Professor, Pharmaceutical Chemistry

Research summary: Protein Machines, Posttranslational Dynamics and Mass Spectrometry

http://msf.ucsf.edu/

Maria Almira Correia

almira.correia@ucsf.edu

Professor in Residence, Cellular and Molecular Pharmacology, Medicine, Pharmacy, Pharmaceutical Chemistry, Cellular & Molecular Pharmacology

Research summary: Structure-Function Relationships and Regulation of Hepatic Hemoproteins

Charles Craik

craik@cgl.ucsf.edu

Professor, Pharmaceutical Chemistry

Research summary: Protein engineering, mutagenesis, heterologous gene expression, enzyme mechanisms and inhibitor design.

http://www.craiklab.ucsf.edu/

Bill DeGrado

william.degrado@ucsf.edu

Professor, Pharmaceutical Chemistry

Research summary: Molecular design as an approach to understanding macromolecule structure and function.

http://www.degradolab.org/

Joe DeRisi

joe@derisilab.ucsf.edu

Hughes Investigator, Professor, Biochemistry and Biophysics

Research summary: Infectious Disease, Genomics

http://derisilab.ucsf.edu/

Tejal Desai

tejal.desai@ucsf.edu

Professor, Physiology, Bioengineering and Therapeutic Sciences

Research summary: Micro and nanofabrication approaches to tissue engineering scaffold design; implantable and oral drug delivery platforms; Surface modification for enhanced biorecognition, targeting, and biocompatibility.

http://bts.ucsf.edu/desai/

Pamela England

england@picasso.ucsf.edu

Associate Professor, Pharmaceutical Chemistry

Research summary: Ion channel structure-function, synaptic plasticity.

http://englandlab.ucsf.edu/

Thomas Ferrin

tef@cgl.ucsf.edu

Professor, Pharmaceutical Chemistry, Bioengineering and Therapeutic Sciences, Director Resource for Biocomputing, Visualization, and Informatics

Research summary: Molecular graphics; scientific visualization; computational chemistry; bioinformatics; structure-based drug design

http://www.cgl.ucsf.edu/

Michael Fischbach

fischbach@fischbachgroup.org

Assistant Professor, Bioengineering and Therapeutic Sciences

Research summary: Identification and characterization of small molecules from microbes; chemical interactions among human-associated microbes and between humans and their microbiome.

http://www.fischbachgroup.org

Robert Fletterick

flett@msg.ucsf.edu

Professor, Biochemistry and Biophysics

Research summary: Structure and function of proteins, using x-ray crystallography and molecular genetics.

http://msg.ucsf.edu/flett

Alan Frankel

frankel@cgl.ucsf.edu

Professor, Biochemistry and Biophysics

Research summary: Assembly and function of RNA-protein complexes; structure and mechanisms of HIV Tat and Rev; HIV-host protein interactions

http://biochemistry.ucsf.edu/labs/frankel/

Danica Galonic Fujimori

fujimori@cmp.ucsf.edu

Assistant Professor, Cellular and Molecular Pharmacology, Pharmaceutical Chemistry

Research summary: Chemical approaches to investigate enzymatic function

http://fujimorilab.ucsf.edu

Zev Gartner

zev.gartner@ucsf.edu

Assistant Professor, Pharmaceutical Chemistry

Research summary: New methods for synthesizing and perturbing functional biological structures

http://www.gartnerlab.ucsf.edu/

John Gross

jdgross@picasso.ucsf.edu

Associate Professor, Pharmaceutical Chemistry

Research summary: Structural biology and mechanism of gene specific translation control; RNA turnover; macromolecular NMR spectroscopy.

http://www.grosslab.ucsf.edu/

Bo Huang

bhuang@picasso.ucsf.edu

Assistant Professor, Pharmaceutical Chemistry

Research summary: Using super-resolution optical microscopy to understand the molecular architecture inside a cell.

http://huanglab.ucsf.edu

Holly Ingraham

holly.ingraham@ucsf.edu

Professor, Cellular and Molecular Pharmacology, Phamacology

Research summary: Gene Expression and Cellular Signalling in Reproductive Development

http://ingrahamlab.ucsf.edu/

Matthew Jacobson

matt@cgl.ucsf.edu

Professor, Pharmaceutical Chemistry

Research summary: Fundamental principles of physical chemistry and biological applications specifically modeling proteins and protein-ligand complexes using physics-based methods

http://francisco.compbio.ucsf.edu/~jacobson/

Thomas James

james@picasso.nmr.ucsf.edu

Professor, Pharmaceutical Chemistry

Research summary: RNA-protein recognition; RNA, DNA and protein structure and dynamics; development of drugs targeting RNA.

http://www.jameslab.ucsf.edu/

David Julius

david.julius@ucsf.edu

Professor, Physiology

Research summary: The Molecular Biology of Nociception and Pain

http://physio.ucsf.edu/julius/

Natalia Jura

natalia.jura@ucsf.edu

Assistant Professor in Residence, Cardiovascular Research Institute

Research summary: Structural basis for Receptor Tyrosine Kinase signaling across the plasma membrane and its regulation by actin cytoskeleton

http://www.cvri.ucsf.edu/~jura

Tanja Kortemme

kortemme@cgl.ucsf.edu

Associate Professor, Bioengineering and Therapeutic Sciences

Research summary: Computational biology, prediction and design of protein interactions and networks, synthetic biology

http://kortemmelab.ucsf.edu/

Nevan Krogan

krogan@cmp.ucsf.edu

Associate Professor, Cellular and Molecular Pharmacology

Research summary: Functional Insights from Genetic and Physical Interaction Maps

http://kroganlab.ucsf.edu

Wendell Lim

lim@cmp.ucsf.edu

Professor, Cellular and Molecular Pharmacology

Research summary: Structure-function studies of potassium channels in mammalian heart and hippocampus.

http://limlab.ucsf.edu/

Jim McKerrow

james.mckerrow@ucsf.edu

Professor, Pathology, Pharmaceutical Chemistry

Research summary: Protease Structure and Biology and Protease Inhibitor Development

http://pathology.ucsf.edu/mckerrow

Susan Miller

smiller@cgl.ucsf.edu

Associate Professor, Pharmaceutical Chemistry

Research summary: Enzyme mechanisms emphasizing redox systems, protein-protein interactions and structure-function relationships of mechanisms of regulation and catalysis.

http://pharmchem.ucsf.edu/faculty/bios/smiller.html

Daniel Minor

daniel.minor@ucsf.edu

Professor, Cardiovascular Research Institute, Biochemistry and Biophysics, Cellular and Molecular Pharmacology

Research summary: Molecular Basis of electrical signalling; Ion channel structure, function, and modulation. Membrane protein structure.

http://www.cvri.ucsf.edu/~dminor/

Geeta Narlikar

geeta.narlikar@ucsf.edu

Associate Professor, Biochemistry and Biophysics

Research summary: Mechanisms of chromatin remodeling

http://biochemistry.ucsf.edu/labs/narlikar/

Paul Ortiz de Montellano

ortiz@cgl.ucsf.edu

Professor of Pharmaceutical Chemistry, and Cellular & Molecular Pharmacology

Research summary: The Chemical Biology of Hemeproteins

www.sacs.ucsf.edu/home/ortiz/index.html

Andrej Sali

sali@salilab.org

Professor, Bioengineering and Therapeutic Sciences

Research summary: Computation grounded in the laws of physics and evolution to study the structure and function of proteins

http://www.salilab.org/

Brian Shoichet

shoichet@cgl.ucsf.edu

Professor, Pharmaceutical Chemistry

Research summary: Molecular docking, structure-based inhibitor discovery, beta-lactamase activity-stability-evolution, and crystallography.

http://shoichetlab.compbio.ucsf.edu

Kevan Shokat

shokat@cmp.ucsf.edu

Professor, Cellular and Molecular Pharmacology

Research summary: Chemical tools for studying cellular signaling cascades; protein engineering; organic synthesis.

http://shokatlab.ucsf.edu/

Xiaokun Shu

xiaokun.shu@ucsf.edu

Assistant Professor, Pharmaceutical Chemistry, Cardiovascular Research Institute

Research summary: Protein design and evolution; Genome engineering; Molecular imaging and medicine

http://shulab.ucsf.edu/

Robert Stroud

stroud@msg.ucsf.edu

Professor, Biochemistry and Biophysics

Research summary: Structure and function of cell-surface receptors; communication between macromolecules; mechanisms of transmembrane signaling; drug design.

http://www.msg.ucsf.edu/stroud/