Chemistry and Chemical Biology
Graduate Program
CCB Students
2008-2009
Advanced Students |
Research Advisor |
Research Interests |
|
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Boyce, Sarah |
Brian Shoichet |
Cytochrome c peroxidase W191G; a model system to interrogate the Dock scoring function |
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Chung, Janet |
Tom James |
Mechanistic study of a small molecule activator that faciliates the maturation of the HIV-1 genome |
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Smithson, David |
R. Kip Guy |
The Search for Reversible Inhibitors of T. brucei Ornithine Decarboxylase - A Comparison of Virtual and High-Throughput Screening |
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Breslow, David |
Jonathan Weissman |
A Flow Cytometry-Based Approach to Quantitative Genetic Interaction Measurements |
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Cruz, Leslie |
Robert Fletterick |
Structural and Functional Studies of Novel Steroid:Androgen Receptor Pairs |
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Henise, Jeffrey |
Jack Taunton |
Development of Irreversible Inhibitors of the Human Mitotic Kinase Nek2 |
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Jones, Brittnee |
John Gross |
RNA recognition by mRNA decapping enzyme Dcp2 |
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Miller, Jason |
Steve Finkbeiner |
Who's the culprit? Deciphering what the toxic protein species is in neurodegenerative Huntington's Disease |
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Widmaier, Daniel |
Chris Voigt |
Engineering the Salmonella Type III Secretion System Fourth Year Students |
| Fifth Year Students | |||
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Borja, Mark |
John Gross |
Structure and dynamics of the yeast mRNA decapping complex by NMR |
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Buser, Karin |
Keith Yamamoto |
The role of Swi/Snf ATPases in transcriptional regulation of GR |
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Crawford, Emily |
Jim Wells |
Labeling of liberated N-termini for proteome-wide detection and characterization of apoptotic caspase substrates |
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Ferreira, Rafaela |
Jim McKerrow Brian Shoichet |
Structure-based design of cruzain inhibitors |
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MacKinnon, Andrew |
Jack Taunton |
Synthesis, target identification, and mechanism of action of a small molecule inhibitor of cotranslational translocation |
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Tavshanjian, Brandon |
Kevan Shokat |
Investigating connections between the phosphoinositide kinase/carbonyl reductase families and mammalian autophagy |
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Williams, Olusegun |
Kevan Shokat |
Developing potent and selective lipid kinase inhibitors |
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Zorn, Julie |
Jim Wells |
Site-directed chemical biology on caspase 1, and the identifcation of selective allosteric inhibitors to caspase 1 |
| Fourth Year Students | |||
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Burden, Brianna |
Warner Greene |
Designing inhibitors of vif that block the degradation of APOBEC3G |
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Canzio, Daniele |
Geeta Narlikar |
Chromatin opening by pioneer transcription factors |
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Gray, Daniel |
Jim Wells |
Engineering apoptosis pathways by employing genetic and protein engineering methods |
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Pillsbury, Marlisa |
Keith Yamamoto |
Working towards understanding the mechanism by which the glucocorticoid receptor confers rhythmic expression of circadian rhythm genes |
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Serafimova, Iana |
Jack Taunton |
Development and mechanism of action of reversible covalent inhibitors that target non catalytic cysteines |
| Third Year Students | |||
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Aglietti, Robin |
John Gross |
Structure and dynamics of UPF1 by NMR spectroscopy |
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Choy, Jonathan |
Adam Renslo Jack Taunton |
Studying kinases in T.brucei using small molecule inhibitors |
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Hertz, Nicholas |
Al Burlingame Kevan Shokat |
Identification of kinase substrates in the mitochondria by covalent capture of thiophosphopeptides and analysis by mass spectrometry based proteomics. |
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Liu, Jennifer |
Zev Gartner |
Synthetic Cell Biology: Dissecting signal integration by individual cells within topologically defined microenvironments |
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Lopez, Michael |
Dave Morgan Kevan Shokat |
Development of chemical tools to study the processes of ubiquitination and deubiquitination of substrate proteins |
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Maglathlin, Rebecca |
Jack Taunton |
Development of reversible covalent inhibitors of protein kinases |
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Miller, Rand |
Jack Taunton |
Probing the limits and utility of cysteine electrophiles in the context of reversible, covalent small-molecule kinase inhibitors. |
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Shiau, Carrie |
Danica Galonic Fujimori |
Development of Chemical Probes for Fe(II) and alpha-KG Dioxygenases |
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Tajon, Cheryl |
Charles Craik |
Proteolytic activation of nanoparticles and devices |
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Wong, Xiuming |
Lily Jan |
Structure, function and trafficking of ion channels |
| Second Year Students | |||
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Ho, Linh |
Eric Verdin |
Studying the role of SirT4. |
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Le, Daniel |
Danica Galonic Fujimori |
Using chemically-modified histone models to understand chromatin epigenetics. |
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Morgan, Charles |
Jim Wells |
Investigating of the cellular biology of crucial caspase substrates using genetic and protein engineering techniques. |
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Myers, Samuel |
Al Burlingame |
Using mass spectrometry to study O-linked glycosylation and other protein post-translational modifications in embryonic stem cells. Optimization of electron transfer dissociation for modified peptides. |
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Ortiz Torres, Idelisse |
Danica Galonic Fujimori |
Development of mechanism based inhibitor for JmjC-domain-containing histone demethylases. |
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Riel-Mehan, Megan |
Kevan Shokat |
Designing and using small molecules that selectively crosslink enzyme-substrate pairs in order to find unknown interactions in signaling pathways. |
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Wiser, Andrew |
Keith Yamamoto |
Studying glucocorticoid induced osteoporosis using genetic approaches. |
| First Year Students | |||
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Jee, Noel | ||
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Kaemmerer, Daniel | ||
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Karpiak, Joel | ||
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Lee, Melody | ||
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Mendez, Aaron | ||
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Nyitray, Crystal | ||
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Ostrem, Jonathan | ||
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Rettenmaier, Justin | ||
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Silber, Amanda | ||
