Chemistry and Chemical Biology
Graduate Program
Areas of Research
Synthetic Chemistry: Charles Craik, Pam England, Danica Galonic Fujimori, Zev Gartner, Stephen Kahl, Paul Ortiz de Montellano, Kevan Shokat, Jack Taunton, James Wells
Biochemistry: Frances Brodsky, Alma Burlingame, Joe DeRisi, Alan Frankel, Holly Ingraham, James McKerrow, Susan Miller, Geeta Narlikar, Peter Walter, Ching C. Wang
Cellular and Molecular Pharmacology: M. Almira Correia, Michael Fischbach, David Julius, Nevan Krogan, Francis Szoka, Jonathan Weissman, Keith Yamamoto
Physical Chemistry and Computational Biology: Patricia Babbitt, Ken Dill, Thomas Ferrin, Matthew Jacobson, Tanja Kortemme, Andrej Sali, Richard Shafer, Brian Shoichet, Chris Voigt
Macromolecular Structure: Dave Agard, Robert Fletterick, John Gross, Bo Huang, Thomas James, Wendell Lim, Dan Minor, Robert Stroud
Faculty Directory
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Dave Agard
Professor of Biochemistry and Biophysics, Pharmaceutical Chemistry; Ph.D.
Steroid Receptor Structure-Function, Protein Folding and Centrosome Structure
Contact Information:
600 16th St., MC 2240
Genentech Hall S412D
San Francisco, CA 94158
Phone: 415.476.2521
Fax: 415.476.1902
Email: agard@msg.ucsf.edu
Website: http://www.msg.ucsf.edu/agard/index.html
Patricia Babbitt
Professor of Biopharmaceutical Sciences and Pharmaceutical Chemistry; Ph.D.
Enzyme evolution and Engineering, Structure/Function Relationships in Enzyme Superfamilies
Contact Information:
1700 4th St., MC 2550
Byers Hall, 508E
San Francisco, CA 94158
Phone: 415.476.3784
Fax: 415.514.4797
Email: babbitt@cgl.ucsf.edu
Website: http://babbittlab.compbio.ucsf.edu/
Frances Brodsky
Professor of Biopharmaceutical Sciences, Pharmaceutical Chemistry, and Microbiology & Immunology; D.Phil.
Molecular Mechanisms of Intracellular Membrane Traffic
Contact Information:
513 Parnassus Ave., HSW 1527, MC 0552
San Francisco, CA 94143-0552
Phone: 415.476.6405
Fax: 415.476.6185
Email: frances.brodsky@ucsf.edu
Website: http://www.ucsf.edu/brodsky/
Alma Burlingame
Professor of Pharmaceutical Chemistry; Ph.D.
Protein Machines, Posttranslational Dynamics and Mass Spectrometry
Contact Information:
600 16th St., MC 2240
Genentech Hall N472G
San Francisco, CA 94158
Phone: 415.476.5641
Fax: 415.476.0688
Email: alb@cgl.ucsf.edu
Website: http://donatello.ucsf.edu
Maria Almira Correia
Professor in Residence of Cellular & Molecular Pharmacology, Medicine, Pharmacy, and Pharmaceutical Chemistry; Ph.D.
Structure-Function Relationships and Regulation of Hepatic Hemoproteins
Contact Information:
600 16th St., MC 2280
Genentech Hall N572F
San Francisco, CA 94158
Phone: 415.476.3992
Fax: 415.476.5292
Email: almira.correia@ucsf.edu
Charles S. Craik
Professor of Biochemistry, Pharmaceutical Chemistry and Cellular & Molecular Pharmacology; Ph.D.
The Chemical Biology of Proteolysis
Contact Information:
600 16th St., MC 2280
Genentech Hall S512C
San Francisco, CA 94158
Phone: 415.476.8146, 476-6757
Fax: 415.502.8298
Email: craik@cgl.ucsf.edu
Website: http://www.craiklab.ucsf.edu/
Joe DeRisi
Professor of Biochemistry & Biophysics; Ph.D.
DNA Microarrays
Contact Information:
1700 4th St., MC 2542
Byers Hall, 403C
San Francisco, CA 94158
Phone: 415.476.4132
Fax: 415.476-0806
Email: joe@derisilab.ucsf.edu
Website: http://derisilab.ucsf.edu/
Ken Dill
Professor of Pharmaceutical Chemistry; Ph.D.
Statistical Mechanics of Biomolecules
Contact Information:
600 16th St., MC 2240
Genentech Hall N472F
San Francisco, CA 94158
Phone: 415.476.9964
Fax: 415.502.4222
Email: dill@maxwell.ucsf.edu
Website: http://www.dillgroup.ucsf.edu/
Pamela England
Associate Professor of Pharmaceutical Chemistry, and Cellular & Molecular Pharmacology; Ph.D.
Chemical Neurobiology: Ion Channel Structure-Function, Synaptic Plasticity
Contact Information:
600 16th St., MC 2280
Genentech Hall N512B
San Francisco, CA 94158
Phone: 415.502.6606
Fax: 415.502.4690
Email: england@picasso.ucsf.edu
Tom Ferrin
Professor of Pharmaceutical Chemistry; Ph.D.
Macromolecular Structure and Function Through Use of Computational Algorithms and Interactive Three-Dimensional Computer Graphics
Contact Information:
600 16th St., MC 2240
Genentech Hall N472E
San Francisco, CA 94158
Phone: 415.476.2299
Fax: 415.502.1755
Email: tef@cgl.ucsf.edu
Website: http://www.cgl.ucsf.edu/home/tef/
Michael Fischbach
Assistant Professor of Bioengineering and Therapeutic Sciences; Ph.D.
Identification and characterization of small molecules from microbes;
chemical interactions among human-associated microbes and between humans and
their microbiome
Contact Information:
1700 4th St., MC 2530
Byers Hall 308C
San Francisco, CA 94158-2330
Tel: .415.514.9435
Fax: 415.514.9736
Email: michael.fischbach@ucsf.edu
Website: http://www.fischbachgroup.org
Robert J. Fletterick
Professor of Biochemistry & Biophysics, and Cellular & Molecular Pharmacology; Ph.D.
Structural Chemistry of Protein Interactions
Contact Information:
600 16th St., MC 2240
Genentech Hall S412E
San Francisco, CA 94158
Phone: 415.476.5080
Fax: 415.476.1902
Email: flett@msg.ucsf.edu
Website: http://www.msg.ucsf.edu/flett/
Alan D. Frankel
Professor of Biochemistry, and Cellular & Molecular Pharmacology; Ph.D.
RNA-Protein Recognition
Contact Information:
600 16th St., MC 2280
Genentech Hall S572C
San Francisco, CA 94158
Phone: 415.476.9994
Fax: 415.502.4315
Email: frankel@cgl.ucsf.edu
Website: http://www.ucsf.edu/frankel/frankel_homepage.html
Danica Galonic Fujimori
Assistant Professor of Cellular & Molecular Pharmacology, and Pharmaceutical Chemistry; Ph.D.
Chemical Approaches to Investigate Enzymatic Function
Contact Information:
600 16th St., MC 2280
Genentech Hall N572B
San Francisco, CA 94158
Phone: 415.514.0147
Fax: 415.514.4857
Email: fujimori@cmp.ucsf.edu
Website: http://fujimorilab.ucsf.edu
Zev Gartner
Assistant Professor of Pharmaceutical Chemistry; Ph.D.
Nucleic acid biochemistry, biomaterials, and synthesis of functional biological structures
Contact Information:
600 16th St., MC 2280
Genentech Hall N512E
San Francisco, CA 94158
Phone: 415.514.9962
Email: zev.gartner@ucsf.edu
Website: http://www.gartnerlab.ucsf.edu/
John Gross
Assistant Professor of Pharmaceutical Chemistry; Ph.D.
Translational Control of Gene Expression; RNA Turnover
Contact Information:
600 16th St., MC 2280
Genentech Hall S512E
San Francisco, CA 94158
Phone 415.514-4402
Fax: 415.502.8298
Email: jdgross@picasso.ucsf.edu
Website: http://www.grosslab.ucsf.edu
Bo Huang
Assistant Professor of Pharmaceutical Chemistry, and Biochemistry & Biophysics; Ph.D.
Super-resolution optical microscopy, macromolecular complex architecture and membrane receptor organization
Contact information:
600 16th St., MC 2280
Genentech Hall S512F
San Francisco, CA 94158
Phone: 415.476.1866
Fax: 415.502.8298
Email: bhuang@picasso.ucsf.edu
Website: http://huanglab.ucsf.edu
Holly Ingraham
Professor of Cellular and Molecular Pharmacology, and Ob/Gyn; Ph.D.
Gene Expression and Cellular Signalling in Reproductive Development
Contact Information:
1550 4th Street GD284E, MC 2611
Rock Hall
University of California, San Francisco
San Francisco, CA. 94143 - 2611
Phone: 415.476.2731
Fax: 415.476.4929
Email: holly.ingraham@ucsf.edu
Website: http://www.ucsf.edu/inglab/
Matthew Jacobson
Associate Professor of Pharmaceutical Chemistry; Ph.D.
Physical Chemistry-based Approaches to Predictive Protein Modeling
Contact Information:
600 16th St., MC 2240
Genentech Hall N472C
San Francisco, CA 94158
Phone: 415.514.9811
Fax: 415.502.1411
Email: matt@cgl.ucsf.edu
Website: http://francisco.compbio.ucsf.edu/~jacobson/
Tom James
Professor of Pharmaceutical Chemistry; Ph.D.
Three Dimensional Structure Determination by NMR
Contact Information:
600 16th St., MC 2280
Genentech Hall S512D
San Francisco, CA 94158
Phone 415.476.1916
Fax: 415.502.4690
Email: james@picasso.ucsf.edu
Website: http://www.jameslab.ucsf.edu/
David J. Julius
Professor and Chair of Physiology; Ph.D.
The Molecular Biology of Nociception and Pain
Contact Information:
600 16th St., MC 2140
Genentech Hall N272E
San Francisco, CA 94158
Phone: 415.476.0431
Fax: 415.502.8644
Email: julius@cmp.ucsf.edu
Website: http://www.ucsf.edu/djlab/
Stephen Kahl
Professor of Pharmaceutical Chemistry; Ph.D.
Synthesis and Evaluation of Cancer Chemotherapeutics
Contact Information:
513 Parnassus Ave., S1122, MC 0446
San Francisco, CA 94143-0446
Phone: 415.476.4684
Fax: 415.476.0688
Email: sbkahl@picasso.ucsf.edu
Tanja Kortemme
Assistant Professor of Biopharmaceutical Sciences, Ph.D.
Design, analysis and evolution of proteins, protein interactions and networks
Contact Information:
1700 4th St., MC2530
Byers Hall, 308E
San Francisco, CA, 94158
Phone: (415) 514-1368
Email: kortemme@cgl.ucsf.edu
Website: http://kortemmelab.ucsf.edu/
Nevan J. Krogan
Assistant Professor of Cellular and Molecular Pharmacology, Ph.D.
Functional Insights from Genetic and Physical Interaction Maps
Contact Information:
1700 4th St., MC 2530
Byers Hall, 308D
San Francisco, CA, 94158
Phone: (415) 476-2980
Fax: (415) 514-2073
Email: krogan@cmp.ucsf.edu
Website: http://kroganlab.ucsf.edu/
Wendell A. Lim
Professor of Cellular & Molecular Pharmacology, and Biochemistry & Biophysics; Ph.D.
The Molecular Logic of Modular Signal Transduction Proteins
Contact Information:
600 16th St., MC 2240
Genentech Hall N412E
San Francisco, CA 94158
Phone: 415.502.8080
Fax: 415.502.8644
Email: lim@cmp.ucsf.edu
Website: http://www.ucsf.edu/limlab
James McKerrow
Professor of Pathology, and Pharmaceutical Chemistry; Ph.D.
Protease Structure and Biology and Protease Inhibitor Development
Contact Information:
1700 4th St., MC 2550
Byers Hall, 508B
San Francisco, CA 94158
Phone: 415.476.2940
Fax: 415.476-9274
Email: jmck@cgl.ucsf.edu
Website: http://www.ucsf.edu/mckerrow/
Susan Miller
Associate Professor of Pharmaceutical Chemistry; Ph.D.
Enzyme Mechanisms and Regulation
Contact Information:
600 16th St., MC 2280
Genentech Hall S512B
San Francisco, CA 94158
Phone: 415.476.7155
Fax: 415.514-3221
Email: smiller@cgl.ucsf.edu
Dan Minor
Associate Professor of Biochemistry & Biophysics; Ph.D.
Investigator, Cardiovascular Research Institute
Molecular Structure and Mechanism of Ion Channel Action, Development of Novel Molecules for Ion Channel Regulation
Contact Information:
1700 4th St., MC 2532
Byers Hall, 303A
San Francisco, CA 94158
phone: 415-514-2551
fax: 415-476-5774
Email: daniel.minor@ucsf.edu
Website: http://www.cvri.ucsf.edu/~dminor
Geeta Narlikar
Assistant Professor of Biochemistry & Biophysics; Ph.D.
Mechanisms of Chromatin Remodeling
Contact Information:
600 16th St., MC 2240
Genentech Hall N412F
San Francisco, CA 94158
Phone: 415.514.0394
Fax: 415.514.4242
Email: gnarlikar@biochem.ucsf.edu
Website: http://biochemistry.ucsf.edu/labs/narlikar/
Paul Ortiz de Montellano
Professor of Pharmaceutical Chemistry, and Cellular & Molecular Pharmacology; Ph.D.
The Chemical Biology of Hemeproteins
Contact Information:
600 16th St., MC 2280
Genentech Hall N572D
San Francisco, CA 94158
Phone: 415.476.2903
Fax: 415.502.4728
Email: ortiz@cgl.ucsf.edu
Website: http://www.sacs.ucsf.edu/home/Ortiz/index.html
Andrej Sali
Professor of Biopharmaceutical Sciences and Pharmaceutical Chemistry; Ph.D.
Computational Study of Structure and Function of Proteins
Contact Information:
1700 4th St., MC 2552
Byers Hall, 503B
San Francisco, CA 94158
Phone: 415.514.4227
Fax: 415.514.4231
Email: sali@salilab.org
Web: http://www.salilab.org
Richard Shafer
Professor of Pharmaceutical Chemistry; Ph.D.
Nucleic Acid Structure and Interactions
Contact Information:
513 Parnassus Ave., S1004, MC 0446
San Francisco, CA 94143-0446
Phone: 415. 476.2761
Fax: 415.476.0688
Email: shafer@cgl.ucsf.edu
Brian Shoichet
Professor of Pharmaceutical Chemistry; Ph.D.
Structure-Based Inhibitor Discovery
Contact Information:
1700 4th St., MC 2550
Byers Hall, 508D
San Francisco, CA 94158
Phone: 415-514-4126
Fax: 415-502-1411
Email: shoichet@cgl.ucsf.edu
Website: http://shoichetlab.compbio.ucsf.edu
Kevan Shokat
Professor of Cellular & Molecular Pharmacology; Ph.D.
Unnatural Ligands for Engineered Proteins: New Tools for Chemical Biology
Contact Information:
600 16th St., MC 2280
Genentech Hall N512D
San Francisco, CA 94158
Phone: 415.514.0472
Fax: 415.514.0822
Email: shokat@cmp.ucsf.edu
Website: http://www.ucsf.edu/shokat
Robert Stroud
Professor of Biochemistry & Biophysics, and Pharmaceutical Chemistry; Ph.D.
Cellular Signaling and Molecular Mechanisms
Contact Information:
600 16th St., MC 2240
Genentech Hall S412C
San Francisco, CA 94158
Phone: 415.476.4224
Fax: 415.476.1902
Email: stroud@msg.ucsf.edu
Website: http://www.msg.ucsf.edu/stroud/
Frank Szoka
Professor of Biopharmaceutical Sciences, and Pharmaceutical Chemistry ; Ph.D.
Gene Therapy and Macromolecular Drug Delivery Systems
Physico-Chemistry of Membranes and Lipid Dispersions
Contact Information:
513 Parnassus Ave., HSE1145D, MC 0446
San Francisco, CA 94143-0446
Phone: 415.476.3895
Fax: 415.476.0688
Email: szoka@cgl.ucsf.edu
Website: http://www.ucsf.edu/fszoka/
Jack Taunton
Associate Professor of Cellular & Molecular Pharmacology, Pharmaceutical Chemistry; Ph.D.
Investigator, Howard Hughes Medical Institute
Molecular Dissection of Cell Function with Electrophilic Chemical Libraries
Contact Information:
600 16th St., MC 2280
Genentech Hall N512F
San Francisco, CA 94158
Phone: 415.514-2004
Fax: 415.476-5292
Email: taunton@cmp.ucsf.edu
Website: http://cmp.ucsf.edu/faculty/pdb_show.html?id=taunton
Christopher Voigt
Associate Professor of Pharmaceutical Chemistry; PhD.
Design and Evolution of Complex Gene Circuits
Contact Information:
1700 4th St., MC 2540
Byers Hall, 408C
San Francisco, CA 94158
Phone: 415. 502-7050
Fax: 415. 502-8298
Email: cavoigt@picasso.ucsf.edu
Website: http://www.voigtlab.ucsf.edu/
Peter Walter
Professor of Biochemistry & Biophysics; Investigator, Howard Hughes Medical Institute; PhD.
Intracellular Signalling; Regulated mRNA Splicing; Protein Sorting
Contact Information:
600 16th St., MC 2200
Genentech Hall N312D
San Francisco CA 94158
Phone: 415.476.5017
Fax: 415.476.5233
Email: pwalter@biochem.ucsf.edu
Website: http://walterlab.ucsf.edu/
Ching C. Wang
Professor of Pharmaceutical Chemistry; Ph.D.
Molecular Approaches to Combatting Infectious Diseases
Contact Information:
600 16th St., MC 2280
Genentech Hall N572C
San Francisco CA 94158
Phone: 415.476.1321
Fax 415.476.3382
Email: ccwang@cgl.ucsf.edu
Website: http://www.sacs.ucsf.edu/home/CCWangLab/
Jonathan Weissman
Professor of Cellular & Molecular Pharmacology, and Biochemistry & Biophysics; Ph.D.
In Vivo Mechanism of Protein Folding and Misfolding
Contact Information:
1700 4th St., MC 2542
Byers Hall, 403B
San Francisco, CA 94158
Phone: 415.502.7642
Fax: 415.502.8644
Email: weissman@cmp.ucsf.edu
Website: http://www.ucsf.edu/jswlab
James Wells
Professor of Cellular & Molecular Pharmacology, Chair of Pharmaceutical Chemistry; Ph.D.
Discovery and Design of Small Molecules that Trigger or Modulate Cellular Processes in Inflammation and Cancer
Contact Information:
1700 4th St., MC 2552
Byers Hall, 503A
San Francisco, CA 94158
Phone: 415.514.4498
Fax: 415.514.4507
Email: jim.wells@ucsf.edu
Website: http://wellslab.ucsf.edu/
Small Molecule Discovery Center: http://smdc.ucsf.edu/
Keith R. Yamamoto
Professor of Cellular & Molecular Pharmacology, and Biochemistry & Biophysics; Ph.D.
Signaling and Transcriptional Activation by Intracellular Receptors
Contact Information:
600 16th St., MC 2280
Genentech Hall S572D
San Francisco, CA 94158
Phone: 415.476.3128
Fax: 415.476.6129
Email: yamamoto@cmp.ucsf.edu
Website: http://www.ucsf.edu/krylab/